genome

noun

ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web
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The 7,100-year-old remains were included in an analysis of genomes from 127 ancient bodies found in the region, researchers said, but were distinct among the findings. Irene Wright, Miami Herald, 2 June 2025 Virginia Tech researchers made this discovery after comparing the genomes of two distinct lineages of bed bugs – one that is suspected to have hitched a ride on a Neanderthal thousands of years ago, and another that stuck with its bat host. Bronwyn Thompson, New Atlas, 28 May 2025 For the study, an international team of scientists analyzed the genomes of 1,537 individuals from 139 ethnic groups in South America and Northeast Eurasia. Sarah Kuta, Smithsonian Magazine, 23 May 2025 Researchers analyzed more than 1,600 ancient genomes spanning the time from 11,000 years ago through the Middle Ages, comparing them with more than 400,000 modern genomes from the U.K. Biobank. Kermit Pattison, Scientific American, 20 May 2025 See All Example Sentences for genome

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Time Traveler
The first known use of genome was in 1926

Browse Nearby Words

Cite this Entry

“Genome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genome. Accessed 6 Jun. 2025.

Medical Definition

genome

noun
ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism
The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works. Lori Oliwenstein, Discover

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