herpes simplex

noun

herpes sim·​plex -ˈsim-ˌpleks How to pronounce herpes simplex (audio)
: either of two diseases caused by herpesviruses (species Human herpesvirus 1 and Human herpesvirus 2 of the genus Simplexvirus) and marked especially by watery blisters on the skin or mucous membranes of the lips, mouth, face, or genital region

Examples of herpes simplex in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
An artist's impression of the herpes simplex virus. Ian Randall, MSNBC Newsweek, 9 July 2025 Of the groups studied, 1,507 people with Alzheimer’s also had herpes simplex virus type 1 (HSV-1), which is the most common cause of cold sores. Khloe Quill, FOXNews.com, 23 May 2025 New research sheds light on the potential connection between herpes simplex 1 and the neurological condition. Julia Ries, Health, 31 May 2025 In the 1980s a number of studies pointed to associations between the onset of Alzheimer's disease and herpes simplex viral infections, but exactly how this very common virus could be influencing neurodegeneration was not clear. Rich Haridy, New Atlas, 25 Feb. 2025 See All Example Sentences for herpes simplex

Word History

Etymology

New Latin, literally, simple herpes

First Known Use

1907, in the meaning defined above

Time Traveler
The first known use of herpes simplex was in 1907

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Cite this Entry

“Herpes simplex.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/herpes%20simplex. Accessed 21 Jul. 2025.

Kids Definition

herpes simplex

noun
herpes sim·​plex -ˈsim-ˌpleks How to pronounce herpes simplex (audio)
: either of two kinds of herpes marked in one case by groups of watery blisters on the skin and mucous membranes (as of the mouth and lips) above the waist and in the other by such blisters on the genitalia

Medical Definition

herpes simplex

noun
herpes sim·​plex -ˈsim-ˌpleks How to pronounce herpes simplex (audio)
: either of two viral diseases caused by herpesviruses of the genus Simplexvirus that are marked especially by watery blisters on the skin or mucous membranes of the lips, mouth, face, or genital region see hsv-1, hsv-2

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