1
: of superior grade or quality
high-grade bonds
2
a
: being near the upper or most favorable extreme of a specified range
b
: medically serious or life-threatening
a high-grade tumor

Examples of high-grade in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
He was pressed into the Yankees’ season-opening rotation due to a rash of injuries, including to ace Gerrit Cole, who underwent season-ending elbow surgery last month, and Luis Gil, who is expected to miss at least two more months with a high-grade lat strain. Peter Sblendorio, New York Daily News, 2 Apr. 2025 Made from high-grade Mulberry silk, the fabric is exceptionally soft and feels rich. Alesandra Dubin, Travel + Leisure, 28 Mar. 2025 She has been recognized for discovering innovative chemotherapy treatments for high-grade invasive brain tumors. Chase Jordan, Charlotte Observer, 27 Mar. 2025 Free agent acquisition Frankie Montas sustained a high-grade right lat strain and was shut down from throwing for 6–8 weeks in mid-February. Ryan Canfield, FOXNews.com, 27 Mar. 2025 See All Example Sentences for high-grade

Word History

First Known Use

1826, in the meaning defined at sense 1

Time Traveler
The first known use of high-grade was in 1826

Cite this Entry

“High-grade.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/high-grade. Accessed 16 Apr. 2025.

Kids Definition

high-grade

adjective
ˈhī-ˈgrād
: of a better grade or quality

Medical Definition

high-grade

adjective
: being near the upper, most serious, or most life-threatening extreme of a specified range
high-grade gliomas
high-grade cervical dysplasia
compare low-grade

More from Merriam-Webster on high-grade

Last Updated: - Updated example sentences
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