hypersensitive

adjective

hy·​per·​sen·​si·​tive ˌhī-pər-ˈsen(t)-s(ə-)tiv How to pronounce hypersensitive (audio)
1
: excessively or abnormally sensitive
2
: abnormally susceptible physiologically to a specific agent (such as a drug or antigen)
hypersensitiveness noun

Examples of hypersensitive in a Sentence

She's hypersensitive about her past. People who are hypersensitive to the chemical may have violent reactions even to small amounts.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Lee was an editor, writer, ringleader and often the initial spark for a new character: What about a blind lawyer who fights crime using his other hypersensitive senses and was kind of a daredevil? Christopher Borrelli, Chicago Tribune, 4 June 2025 What used to be a politics of tolerance and inclusion is now seen—often rightly—as obsessed with identity, hypersensitive to offense, and incapable of self-criticism. MSNBC Newsweek, 20 May 2025 Only 14 percent of people who reported being extremely hypersensitive to cold had varicose veins. Tom Gavin, EverydayHealth.com, 15 Apr. 2025 IgE can bind to the surface of mast cells or basophils (types of white blood cells) and trigger hypersensitive reactions in response to allergens. Suchandrima Bhowmik, Health, 8 Sep. 2024 See All Example Sentences for hypersensitive

Word History

First Known Use

1871, in the meaning defined at sense 1

Time Traveler
The first known use of hypersensitive was in 1871

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Cite this Entry

“Hypersensitive.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hypersensitive. Accessed 7 Jun. 2025.

Kids Definition

hypersensitive

adjective
hy·​per·​sen·​si·​tive ˌhī-pər-ˈsen(t)-sət-iv How to pronounce hypersensitive (audio)
-ˈsen(t)-stiv
: very sensitive especially to an abnormal degree
hypersensitiveness noun

Medical Definition

hypersensitive

adjective
hy·​per·​sen·​si·​tive ˌhī-pər-ˈsen(t)-sət-iv, -ˈsen(t)-stiv How to pronounce hypersensitive (audio)
1
: excessively or abnormally sensitive
2
: abnormally susceptible physiologically to a specific agent (as a drug or antigen)
hypersensitiveness noun
hypersensitivity noun
plural hypersensitivities

More from Merriam-Webster on hypersensitive

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