imipenem
noun
im·i·pen·em
ˌi-mə-ˈpe-nəm 
: a semisynthetic carbapenem antibiotic C12H17N3O4S·H2O that is derived from a bacterium (Streptomyces cattleya) and is effective against gram-negative and gram-positive bacteria
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An independent data monitoring committee recommended the halt, as the study met its primary endpoint of showing the drug was non-inferior to a combination of the antibiotics imipenem and cilastatin.
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Alex Knapp, Forbes.com, 28 May 2025
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Alex Knapp, Forbes.com, 28 May 2025
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“Imipenem.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/imipenem. Accessed 6 Jun. 2025.
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imipenem
noun
im·i·pen·em
ˌim-ə-ˈpen-əm
: a semisynthetic beta-lactam C12H17N3O4S·H2O that is derived from an antibiotic produced by a bacterium of the genus Streptomyces (S. cattleya) and is effective against gram-negative and gram-positive bacteria
Note: Because imipenem is hydrolyzed by a dipeptidase in the kidney, it is administered with cilastatin, an inhibitor of this enzyme.
Five days before admission, the patient was evaluated by an infectious-disease specialist and readmitted to the other hospital for intravenous administration of a three-day course of imipenem-cilastatin …—Stephen I. Pelton et al., The New England Journal of Medicine
Stephen I. Pelton et al., The New England Journal of MedicineLove words? Need even more definitions?
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