immune system

noun

: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), macrophages, lymphocytes including the B cells and T cells, and antibodies

Examples of immune system in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
When this happens, the immune system doesn't generate protective antibodies against the bacterium, and inflammation ratchets up. ArsTechnica, 11 July 2025 Several people raised their hands Wednesday to say recent surgeries and other health problems had left them with weak immune systems. Blake Nelson, San Diego Union-Tribune, 10 July 2025 Multiple exposures to the SARS-CoV-2 spike proteins via either vaccination or natural infection have helped our immune systems go around block, so to speak, quite a few times. Bruce Y. Lee, Forbes.com, 8 July 2025 Anti-inflammatory properties: Taking spirulina reduces inflammation (immune system activity), which may help with allergy symptoms. Mark Gurarie, Verywell Health, 8 July 2025 See All Example Sentences for immune system

Word History

First Known Use

circa 1919, in the meaning defined above

Time Traveler
The first known use of immune system was circa 1919

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Cite this Entry

“Immune system.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/immune%20system. Accessed 21 Jul. 2025.

Kids Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, lymphocytes, and antibodies

Medical Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), lymphocytes including the B cells and T cells, and antibodies

More from Merriam-Webster on immune system

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