investigational

adjective

in·​ves·​ti·​ga·​tion·​al in-ˌve-stə-ˈgā-sh(ə-)nəl How to pronounce investigational (audio)
1
: of or relating to investigation
investigational activities
2
: relating to or being a drug or medical procedure that is not approved for general use but is under investigation in clinical trials regarding its safety and efficacy
an investigational new drug

Examples of investigational in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Deep brain stimulation and other surgical implants have long been used in neuropsychiatric research as an investigational treatment in cases of severe mental illness, including treatment-resistant depression. Naveen Rao, Forbes.com, 2 Apr. 2025 The company plans to submit three investigational new drug applications to the FDA within the next 12 to 24 months, starting with HWK-007 for solid tumors in the second half of 2025. Quartz Intelligence Newsroom, Quartz, 28 Mar. 2025 The January 25 procedure took place through the US Food and Drug Administration’s Expanded Access pathway, often known as compassionate use, which allows patients with life-threatening conditions to access investigational medical products. Nadia Kounang, CNN, 7 Feb. 2025 The company recently announced that the FDA has granted fast track designation to its investigational biologic – Posdinemab – for treating patients with early Alzheimer’s disease. Trefis Team, Forbes, 10 Jan. 2025 See All Example Sentences for investigational

Word History

First Known Use

1905, in the meaning defined at sense 1

Time Traveler
The first known use of investigational was in 1905

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Cite this Entry

“Investigational.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/investigational. Accessed 16 Apr. 2025.

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