methadone

noun

meth·​a·​done ˈme-thə-ˌdōn How to pronounce methadone (audio)
variants or less commonly methadon
: a synthetic addictive narcotic drug C21H27NO used especially in the form of its hydrochloride for the relief of pain and as a substitute narcotic in the treatment of heroin addiction

Examples of methadone in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
This could include easy access to naloxone and medication for addiction treatment like buprenorphine or methadone. Jasmine Laws, MSNBC Newsweek, 15 May 2025 According to the Palm Beach Post, Andriano died as a result of an overdose of fentanyl, methadone and alprazolam in a West Palm Beach, Florida hotel room. Adam Sabes, FOXNews.com, 29 Apr. 2025 The official cause of death was the combined toxic effects of fentanyl, methadone and amphetamines, along with recent cocaine use, People reports. Katie Atkinson, Billboard, 17 Apr. 2025 This could be a godsend for those who don't live near a clinic since those patients must pick up new methadone doses daily. Dan Primack, Axios, 13 Dec. 2024 See All Example Sentences for methadone

Word History

Etymology

methyl + amino + diphenyl + -one

First Known Use

1947, in the meaning defined above

Time Traveler
The first known use of methadone was in 1947

Browse Nearby Words

Cite this Entry

“Methadone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/methadone. Accessed 4 Jun. 2025.

Kids Definition

methadone

noun
meth·​a·​done ˈmeth-ə-ˌdōn How to pronounce methadone (audio)
variants also methadon
: a narcotic drug C21H27NO that is used to replace heroin in the treatment of heroin addiction

Medical Definition

methadone

noun
meth·​a·​done ˈmeth-ə-ˌdōn How to pronounce methadone (audio)
variants also methadon
: a synthetic addictive narcotic drug used especially in the form of its hydrochloride C21H27NO·HCl for the relief of pain and as a substitute narcotic in the treatment of heroin addiction

called also amidone

More from Merriam-Webster on methadone

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