off-label

adjective

off-la·​bel ˈȯf-ˌlā-bəl How to pronounce off-label (audio)
: of, relating to, or being a drug used to treat a condition for which it has not been officially approved

Examples of off-label in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Sometimes they are also used off-label, for treatment-resistant depression, or catatonia, a syndrome that can cause a patient to move in unusual ways, become immobile or stop talking. Christina Caron, New York Times, 27 Mar. 2025 Bhattacharya responded that the NIH should fund research to look at off-patent, off-label uses of drugs. Victoria Knight, Axios, 5 Mar. 2025 Both can treat Type 2 diabetes, and became widely known after celebrities began using it off-label for weight loss. Angel Saunders, People.com, 28 Feb. 2025 Oral minoxidil: Low-dose oral minoxidil is sometimes prescribed off-label for male- and female-pattern hair loss.6 4. Kelly Burch Published, Verywell Health, 25 Feb. 2025 See All Example Sentences for off-label

Word History

First Known Use

1987, in the meaning defined above

Time Traveler
The first known use of off-label was in 1987

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Cite this Entry

“Off-label.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/off-label. Accessed 16 Apr. 2025.

Medical Definition

off-label

adjective
off-la·​bel ˌȯf-ˌlā-bəl How to pronounce off-label (audio)
: of, relating to, or being an approved drug legally prescribed or a medical device legally used by a physician for a purpose (as the treatment of children or of a certain disease or condition) for which it has not been specifically approved (as by the United States Food and Drug Administration)
the off-label use of oral contraceptives to treat dysmenorrhea
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