serotonin

noun

se·​ro·​to·​nin ˌsir-ə-ˈtō-nən How to pronounce serotonin (audio)
ˌser-
: a phenolic amine neurotransmitter C10H12N2O that is a powerful vasoconstrictor and is found especially in the brain, blood serum, and gastric mucous membrane of mammals

Examples of serotonin in a Sentence

Recent Examples on the Web
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Others point to inflammation, the way the brain processes sensory input, and changes in serotonin levels – which play a key role in activating migraine. Danielle Wilhour, The Conversation, 10 July 2025 Plus, studies have shown that the gut also controls up to 90% of our serotonin production, and can have a marked impact on mood regulation. Morgan Fargo, Vogue, 9 July 2025 Research from the study Embrace the Sun with Dr. Grant Lambert shows brain serotonin production increases along with several other health benefits linked directly to sunlight exposure. Charell G. Coleman, Forbes.com, 1 July 2025 Bright, overhead lighting stimulates serotonin production, enhancing alertness and boosting our mood and energy levels, perfect for kitchens and workspaces, but not ideal for intimate social settings. Sophie Flaxman, Better Homes & Gardens, 15 June 2025 See All Example Sentences for serotonin

Word History

Etymology

sero- + ton(ic) entry 2 or tone entry 1 + -in entry 1, probably after angiotonin, earlier name for angiotensin — more at angiotensin

Note: Term introduced by Maurice M. Rapport, Arda Alden Green and Irvine H. Page in "Crystalline serotonin," Science, vol. 108, Issue 2804 (September 24, 1948), pp. 329-330: "The general behavior of the crystalline substance is suggestive of its homogeneity. We would like provisionally to name it serotonin, which indicates that its source is serum and its activity is one of causing constriction."

First Known Use

1948, in the meaning defined above

Time Traveler
The first known use of serotonin was in 1948

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Cite this Entry

“Serotonin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/serotonin. Accessed 20 Jul. 2025.

Medical Definition

serotonin

noun
se·​ro·​to·​nin ˌsir-ə-ˈtō-nən How to pronounce serotonin (audio) ˌser- How to pronounce serotonin (audio)
: a phenolic amine neurotransmitter C10H12N2O that is a powerful vasoconstrictor and is found especially in the brain, blood serum, and gastric mucous membrane of mammals

called also 5-HT, 5-hydroxytryptamine

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