tryptophan

noun

tryp·​to·​phan ˈtrip-tə-ˌfan How to pronounce tryptophan (audio)
variants or less commonly tryptophane
: a crystalline essential amino acid C11H12N2O2 that is widely distributed in proteins

Examples of tryptophan in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
As for the emerging supplements with little research, some showed the most promise in early studies: Folic acid, lavender, zinc, tryptophan, rhodiola and lemon balm. New Atlas, 14 July 2025 Your body turns tryptophan into serotonin, which has many roles—like mood. Ross Phan, Verywell Health, 10 July 2025 The transdermal stress solution absorbs the water-soluble molecules through your skin to calm and restore with bioavailable magnesium, potassium, vitamin B6 and amino acid tryptophan. Celia Shatzman, Forbes.com, 29 June 2025 But the production of melatonin relies on tryptophan, an amino acid that people need to get from nutrients because the body can’t produce them, said St-Onge, who is also a professor of nutritional medicine at Columbia University. Madeline Holcombe, CNN Money, 23 May 2025 See All Example Sentences for tryptophan

Word History

Etymology

borrowed from German Tryptophan, from tryptisch tryptic + -o- -o- + -phan -phane

First Known Use

1890, in the meaning defined above

Time Traveler
The first known use of tryptophan was in 1890

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Cite this Entry

“Tryptophan.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/tryptophan. Accessed 24 Jul. 2025.

Kids Definition

tryptophan

noun
tryp·​to·​phan ˈtrip-tə-ˌfan How to pronounce tryptophan (audio)
: an amino acid that is found in many proteins and is necessary for life but cannot be manufactured by the human body and must be obtained in food

Medical Definition

tryptophan

noun
tryp·​to·​phan ˈtrip-tə-ˌfan How to pronounce tryptophan (audio)
variants also tryptophane
: a crystalline essential amino acid C11H12N2O2 that is widely distributed in proteins
abbreviation Trp

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